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Membrane dynamics and cation handling in ferroptosis.
Physiology 39, 73-87 (2024)
Ferroptosis, a regulated cell death hallmarked by excessive lipid peroxidation, is implicated in various (patho)physiological contexts. During ferroptosis, lipid peroxidation leads to a diverse change in membrane properties and the dysregulation of ion homeostasis via the cation channels, ultimately resulting in plasma membrane rupture. This review illuminates cellular membrane dynamics and cation handling in ferroptosis regulation.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Cell Death ; Ion Channels ; Lipid Peroxidation ; Oxidative Stress ; Piezo1; Glutathione-peroxidase 4; Persister Cancer-cells; Mixed Lineage Kinase; Lipid-peroxidation; Oxidative Stress; Ion Channels; Oxidized Phospholipids; Nlrp3 Activation; Domain-like; Death
ISSN (print) / ISBN
1548-9213
e-ISSN
1548-9221
Zeitschrift
Physiology
Quellenangaben
Band: 39,
Heft: 2,
Seiten: 73-87
Verlag
American Physiological Society
Verlagsort
6120 Executive Blvd, Suite 600, Rockville, Md, United States
Nichtpatentliteratur
Publikationen
Institut(e)
Institute of Metabolism and Cell Death (MCD)
Förderungen
MEXT | Japan Society for the Promotion of Science (JSPS)
Lotte Research Promotion Grant
JSPS KAKENHI
Takeda Science Foundation
Lotte Research Promotion Grant
JSPS KAKENHI
Takeda Science Foundation