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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Physiologically based persistent organic pollutant accumulation in pig tissues and their edible safety differences: An in vivo study.
Food Chem. 132, 1830-1835 (2012)
As one of the most important animal food sources, pigs are an important model in the assessment of human exposure to persistent organic pollutants (POPs). In the present study, the distribution of the administrated polychlorodibenzo-p-dioxin/furan (PCDD/F)–polychlorinated biphenyl (PCB) mixture and polybrominated diphenyl ethers (PBDEs) in the different tissues of pigs, including liver, lung, kidney, subcutaneous fat, mesentery and muscle, for understanding the physiologically based pollutant accumulation in these tissues and their edible safety was investigated. It was found that liver had a much higher potential to accumulate PCDD/Fs and dioxin-like pollutants like PCB-126 than the other tissues, but it did not specifically concentrate PBDE congeners as compared to the other tissues. The different PCDD/F congeners and PCB-126 followed a similar distribution pattern in the different tissues; also the different PBDE congeners have the similar pattern in these tissues. The liver’s higher concentrating potency for dioxin-like pollutants may result from its detoxification function, however, it can concentrate dioxin-like pollutants but not PBDEs may suggest that it is the toxicity but not lipophilic property of these POPs dominated their accumulation in liver tissues. Also the result suggested that liver is a high-risk edible tissue for dioxin-like pollutants. In conclusion, the present study suggested that physiologically based assessments are necessary for evaluating edible tissue safety in animal source foods.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Polychlorodibenzo-p-dioxin/furan; Polychlorinated biphenyl; Polybrominated diphenyl ether; Pig tissues; Liver; Food safety
ISSN (print) / ISBN
0308-8146
e-ISSN
1873-7072
Zeitschrift
Food Chemistry
Quellenangaben
Band: 132,
Heft: 4,
Seiten: 1830-1835
Verlag
Elsevier
Verlagsort
Amsterdam [u.a.] ; Jena
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
PPM-MEX-Molecular EXposomics (MEX)