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Assessing cancer risks of low-dose radiation.
Nat. Rev. Cancer 9, 596-604 (2009)
Ionizing radiation is considered a non-threshold carcinogen. However, quantifying the risk of the more commonly encountered low and/or protracted radiation exposures remains problematic and subject to uncertainty. Therefore, a major challenge lies in providing a sound mechanistic understanding of low-dose radiation carcinogenesis. This Perspective article considers whether differences exist between the effects mediated by high- and low-dose radiation exposure and how this affects the assessment of low-dose cancer risk.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
30.762
5.040
91
155
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
atomic-bomb survivors; double-strand breaks; ionizing-radiation; dna-damage; in-vivo; gene-expression; hyper-radiosensitivity; telomere dysfunction; human-cells; interventional radiology
Sprache
englisch
Veröffentlichungsjahr
2009
HGF-Berichtsjahr
2009
ISSN (print) / ISBN
1474-175X
e-ISSN
1474-1768
Zeitschrift
Nature Reviews - Cancer
Quellenangaben
Band: 9,
Heft: 8,
Seiten: 596-604
Verlag
Nature Publishing Group
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30202 - Environmental Health
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er)
Radiation Sciences
PSP-Element(e)
G-500200-001
G-501100-004
G-501100-004
DOI
10.1038/nrc2677
Scopus ID
67749103618
PubMed ID
19629073
Erfassungsdatum
2009-11-20