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How to build the virtual cell with artificial intelligence: Priorities and opportunities.
Cell 187, 7045-7063 (2024)
Cells are essential to understanding health and disease, yet traditional models fall short of modeling and simulating their function and behavior. Advances in AI and omics offer groundbreaking opportunities to create an AI virtual cell (AIVC), a multi-scale, multi-modal large-neural-network-based model that can represent and simulate the behavior of molecules, cells, and tissues across diverse states. This Perspective provides a vision on their design and how collaborative efforts to build AIVCs will transform biological research by allowing high-fidelity simulations, accelerating discoveries, and guiding experimental studies, offering new opportunities for understanding cellular functions and fostering interdisciplinary collaborations in open science.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Ai ; Ml ; Cell Biology ; Virtual Cell; Model; Expression; Atlas; Prediction; Biology
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2024
Prepublished im Jahr
0
HGF-Berichtsjahr
2024
ISSN (print) / ISBN
0092-8674
e-ISSN
1097-4172
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 187,
Heft: 25,
Seiten: 7045-7063
Artikelnummer: ,
Supplement: ,
Reihe
Verlag
Cell Press
Verlagsort
Cambridge, Mass.
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
Hochschulort
Fakultät
Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30205 - Bioengineering and Digital Health
Forschungsfeld(er)
Enabling and Novel Technologies
PSP-Element(e)
G-503800-001
Förderungen
Wallenberg Foundation
Cancer Cell Map Initiative (NCI Center for Cancer Systems Biology)
Bridge2AI Program (NIH Common Fund)
Schmidt Futures
GSK
Zuckerberg Initiative
Stanford Data Applications Initiative
NSF
Stanford Institute for Human-Centered AI, Chan Zuckerberg Initiative
Copyright
Erfassungsdatum
2024-12-17