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Sandforth, L. ; Kullmann, S. ; Sandforth, A. ; Fritsche, A. ; Jumpertz von Schwartzenberg, R. ; Stefan, N. ; Birkenfeld, A.L.

Prediabetes remission to reduce the global burden of type 2 diabetes.

Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2025.01.004 (2025)
Article in press DOI PMC
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Prediabetes is a highly prevalent and increasingly common condition affecting a significant proportion of the global population. The heterogeneous nature of prediabetes presents a challenge in identifying individuals who particularly benefit from lifestyle or other therapeutic interventions aiming at preventing type 2 diabetes (T2D) and associated comorbidities. The phenotypic characteristics of individuals at risk for diabetes are associated with both specific risk profiles for progression and a differential potential to facilitate prediabetes remission and reduce the risk of future T2D. This review examines the current definition and global prevalence of prediabetes and evaluates the potential of prediabetes remission to reduce the alarming increase in the global burden of T2D.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Normal Glucose Tolerance ; Obesity ; Prediabetes ; Remission ; Type 2 Diabetes
Sprache englisch
Veröffentlichungsjahr 2025
HGF-Berichtsjahr 2025
ISSN (print) / ISBN 1043-2760
e-ISSN 1879-3061
Zeitschrift Trends in Endocrinology and Metabolism
Verlag Elsevier
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes Research and Metabolic Diseases (IDM)
POF Topic(s) 90000 - German Center for Diabetes Research
Forschungsfeld(er) Helmholtz Diabetes Center
PSP-Element(e) G-502400-001
DOI 10.1016/j.tem.2025.01.004
Scopus ID 85217956303
PubMed ID 39955249
Erfassungsdatum 2025-04-11
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