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Parikh, R.M.* ; Saboo, B.* ; Misra, A.* ; Basit, A.* ; Aravind, S.R.* ; Bhowmik, B.* ; Schwarz, P.E. ; Dhatariya, K.* ; Khunti, K.* ; Joshi, S.* ; Gupta, S.* ; Gupta, A.* ; Chawla, M.* ; Phatak, S.* ; Kalra, S.* ; Khan, A.* ; Mohan, V.*

Ahmedabad declaration: A framework to combat growing epidemic of young-onset type 2 diabetes in Asia.

Diabet. Metab. Syndr. Clin. Res. Rev. 19:103205 (2025)

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AIM: Rising prevalence of Type 2 Diabetes (T2D) among young Asians has emerged as a public health crisis that threatens the long-term health, economic stability, and productivity of nations across Asia (1). Early-onset T2D poses unique challenges, including higher rates of undiagnosed cases, more aggressive disease progression, an increased risk of chronic complications and higher mortality (2). Hyperglycemia during the reproductive age especially among the female population can potentially have transgenerational impact through epigenetic changes. METHODS: A comprehensive search was conducted on PubMed with a combination of relevant keywords. A preliminary draft prepared after review of literature was electronically circulated among a panel of 64 experts from various parts of the region and representatives of the participating organizations - Diabetes India (www.diabetesindia.org.in) and the Diabetes Asia Study Group (DASG, www.da-sg.org). RESULTS: This Ahmedabad Declaration outlines the scale of the problem, its root causes, and a comprehensive action plan for Asian populations. The objectives of this declaration include raising awareness, addressing systemic barriers, and advocating for evidence-based policies and interventions, limited to people with T2D. Through collaborative efforts, we aim to mitigate the growing burden of diabetes in young Asians and secure a healthier future.

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