Loft, A.* ; Emont, M.P.* ; Weinstock, A.* ; Divoux, A.* ; Ghosh, A.* ; Wagner, A.* ; Hertzel, A.V.* ; Maniyadath, B.* ; Deplancke, B.* ; Liu, B.* ; Scheele, C.* ; Lumeng, C.* ; Ding, C.* ; Ma, C.* ; Wolfrum, C.* ; Strieder-Barboza, C.* ; Li, C.* ; Truong, D.D.* ; Bernlohr, D.A.* ; Stener-Victorin, E.* ; Kershaw, E.E.* ; Yeger-Lotem, E.* ; Shamsi, F.* ; Hui, H.X.* ; Camara, H.* ; Zhong, J.* ; Kalucka, J.* ; Ludwig, J.A.* ; Semon, J.A.* ; Jalkanen, J.* ; Whytock, K.L.* ; Dumont, K.D.* ; Sparks, L.M.* ; Muir, L.A.* ; Fang, L.* ; Massier, L. ; Saraiva, L.R.* ; Beyer, M.D.* ; Jeschke, M.G.* ; Mori, M.A.* ; Boroni, M.* ; Walsh, M.J.* ; Patti, M.E.* ; Lynes, M.D.* ; Blüher, M. ; Rydén, M.* ; Hamda, N.* ; Solimini, N.L.* ; Mejhert, N.* ; Gao, P.* ; Gupta, R.K.* ; Murphy, R.* ; Pirouzpanah, S.* ; Corvera, S.* ; Tang, S.* ; Das, S.K.* ; Schmidt, S.F.* ; Zhang, T.* ; Nelson, T.M.* ; O'Sullivan, T.E.* ; Efthymiou, V.* ; Wang, W.* ; Tong, Y.* ; Tseng, Y.H.* ; Mandrup, S.* ; Rosen, E.D.*
Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution.
Nat. Metab. 7, 875-894 (2025)
Adipose tissue (AT) is a complex connective tissue with a high relative proportion of adipocytes, which are specialized cells with the ability to store lipids in large droplets. AT is found in multiple discrete depots throughout the body, where it serves as the primary repository for excess calories. In addition, AT has an important role in functions as diverse as insulation, immunity and regulation of metabolic homeostasis. The Human Cell Atlas Adipose Bionetwork was established to support the generation of single-cell atlases of human AT as well as the development of unified approaches and consensus for cell annotation. Here, we provide a first roadmap from this bionetwork, including our suggested cell annotations for humans and mice, with the aim of describing the state of the field and providing guidelines for the production, analysis, interpretation and presentation of AT single-cell data.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Insulin-resistance; Regional-variation; Brown; Fat; Distinct; Beige; Gamma; Identification; Adipocytes; Reveals
Keywords plus
Sprache
englisch
Veröffentlichungsjahr
2025
Prepublished im Jahr
0
HGF-Berichtsjahr
2025
ISSN (print) / ISBN
2522-5812
e-ISSN
2522-5812
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 7,
Heft: 5,
Seiten: 875-894
Artikelnummer: ,
Supplement: ,
Reihe
Verlag
Springer
Verlagsort
London
Tag d. mündl. Prüfung
0000-00-00
Betreuer
Gutachter
Prüfer
Topic
Hochschule
Hochschulort
Fakultät
Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
Institut(e)
Helmholtz Institute for Metabolism, Obesity and Vascular Research (HI-MAG)
POF Topic(s)
30201 - Metabolic Health
Forschungsfeld(er)
Helmholtz Diabetes Center
PSP-Element(e)
G-506509-001
G-506501-001
Förderungen
National Institutes of Health
Sygeforsikring 'danmark'
Lundbeck Foundation
The Danish National Research Foundation
Copyright
Erfassungsdatum
2025-05-15