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Prinz, J.* ; Nagel, G.* ; Dekkers, S.* ; van Someren, E.P.* ; Adam, V.* ; Battista, V.D.* ; Suarez-Merino, B.* ; Wohlleben, W.* ; Persson, M.* ; Baun, A.* ; Schmid, O. ; Haase, A.*

HARMLESS early warning system for advanced materials.

Adv. Sustain. Syst., DOI: 10.1002/adsu.202500217 (2025)
Verlagsversion Forschungsdaten DOI
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
Advanced Materials (AdMa) play a crucial role for numerous strategies that address global challenges. They are being developed fast, making it increasingly challenging for regulation to keep pace with innovation. Existing frameworks, which are either not designed for AdMa or lack adequate filtering to identify AdMa of high concern, do not (yet) effectively support regulatory preparedness. The HARMLESS Early Warning System (EWS), in contrast, is a practically applicable tool for screening plenty of materials in a reasonable time. It is organized in two tiers, each underpinned by a specific methodology and facilitated by a dedicated online tool. The initial Tier 0 categorizes the materials using the Advanced Materials Earliest Assessment (AMEA) tool. Tier 1 first screens materials asking only 15 questions and is ideal for data-poor materials at early innovation stages. These questions cover issues related to human/ environmental exposure and hazard, sustainability and applicability of existing regulations. In a more elaborated version, experimental testing based on New Approach Methodologies (NAMs) is suggested. As outcome, the user is provided with 1) material-related concerns, 2) prioritization of AdMa and 3) recommendations for (regulatory) follow-up actions. Data from two industrial case studies is presented to demonstrate the applicability of the HARMLESS EWS.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Advanced Materials ; Early Warning System ; Regulatory Preparedness ; Risk Assessment ; Safe-and Sustainable-by-design ; Sustainability; Nanomaterials; Tool
ISSN (print) / ISBN 2366-7486
e-ISSN 2366-7486
Zeitschrift Advanced Sustainable Systems
Verlag Wiley
Verlagsort Postfach 101161, 69451 Weinheim, Germany
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Lung Health and Immunity (LHI)
Förderungen European Union
HORIZON EUROPE Framework Programme