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Fasting-regulated mechanisms in inter-organ crosstalk.

Curr. Opin. Endocr. Metab. Res. 36:100540 (2024)
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Open Access Hybrid
Creative Commons Lizenzvertrag
The adaptation to changing environmental cues represents a key prerequisite for the survival of an organism. Mammals, including humans, have evolved intricate endocrine signals to convey information about the nutritional status to individual organs, cells, and eventually the cell nucleus, to trigger appropriate molecular-metabolic responses. To this end, mounting a proper fasting response is determined by not only intra-organ adaptations but also inter-tissue crosstalk mechanisms that orchestrate whole-body energy homeostasis under nutrient-deprived conditions. Here, we shortly summarize recent advances in our current understanding of the key processes driving the adaptive response to fasting with a focus on the crosstalk between the adipose tissue and liver ketogenesis.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Sprache englisch
Veröffentlichungsjahr 2024
HGF-Berichtsjahr 2025
ISSN (print) / ISBN 2451-9650
e-ISSN 2451-9650
Quellenangaben Band: 36, Heft: , Seiten: , Artikelnummer: 100540 Supplement: ,
Verlag Elsevier
Begutachtungsstatus Peer reviewed
POF Topic(s) 90000 - German Center for Diabetes Research
Forschungsfeld(er) Helmholtz Diabetes Center
PSP-Element(e) G-501900-251
Erfassungsdatum 2025-07-28