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Liu, J.* ; Grapin-Botton, A.

Benchmarking in vivo and in vitro gene co-expression networks enables efficient β-like cell differentiation.

Dev. Cell 61, 229-231 (2026)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
In this issue of Developmental Cell, Yu et al.1 reconstruct human embryonic gene co-expression networks (GCNs) that guide pancreatic endocrine lineage specification. Benchmarking stem cell-derived islet (SC-islet) differentiation protocols against fetal human pancreatic cells reveals early regulatory divergences, thereby enabling the design of a protocol with improved β-like cell production.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Editorial
ISSN (print) / ISBN 1534-5807
e-ISSN 1878-1551
Zeitschrift Developmental Cell
Quellenangaben Band: 61, Heft: 2, Seiten: 229-231 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort 50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Pancreatic Islet Research (IPI)