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Mühlberg, K. ; Schürfeld, R.* ; Kieser, P.* ; Uhlemann, S.* ; Stumvoll, M.* ; Scheinert, D.* ; Blüher, M. ; Fasshauer, M.* ; Ebert, T.*

An adipocytokine signature improves diagnostic accuracy for people living with lipoedema.

Br. J. Dermatol., DOI: 10.1093/bjd/ljag103 (2026)
Verlagsversion DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
Lipoedema is a chronic adipose tissue disorder often misdiagnosed as obesity due to overlapping symptoms and a lack of biomarkers. In this study, we analysed 13 adipocytokines in 79 women and identified chemerin, FGF21 and adiponectin as key biomarkers for distinguishing lipoedema. Decision tree models achieved up to 95% sensitivity, supporting the potential of these biomarkers for improving diagnostic accuracy, particularly in women with overweight or obesity.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Letter to the Editor
ISSN (print) / ISBN 0007-0963
e-ISSN 1365-2133
Zeitschrift British Journal of Dermatology - BJD
Verlag Wiley
Verlagsort Great Clarendon St, Oxford Ox2 6dp, England
Begutachtungsstatus Peer reviewed
Institut(e) Helmholtz Institute for Metabolism, Obesity and Vascular Research (HI-MAG)
Förderungen AstraZeneca
University Leipzig
Karolinska Institutet Research Foundation
Karolinska Institutet
European Foundation for the Study of Diabetes
Novo Nordisk
German Research Foundation
German Diabetes Association