The identification of ubiquitous risk factors determining long-term morbidity is crucial in infants born prematurely when aiming to develop prevention strategies. In a cohort of deeply phenotyped infants born before 32 weeks gestational age, we successfully demonstrate that exposure to fine particulate matter during pregnancy is associated with increased odds of preeclampsia and altered birth weight percentiles, highlighting potential underlying effects on vascular and metabolic pathology in relation to the degree of immaturity.
FörderungenHelmholtz Foundation and the Helmholtz Zentrum Mnchen International Research Group "Role of BMP signaling", Helmholtz Foundation (Federal Ministry of Education and Research in Germany Research Training Group "Targets in Toxicology" of the German Science and Research Organisation (DFG) Stiftung AtemWeg (LSS AIRR) Deutsche Forschungsgemeinschaft