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Diósdi, A.* ; Theis, F.J. ; Horvath, P.

Towards 3D-oid models that integrate molecular, morphological and spatial cellular features.

Nat. Rev. Mol. Cell Biol., DOI: 10.1038/s41580-026-01025-4 (2026)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Methods to study cellular omics, morphology and spatial context evolved independently, yet evidence shows their integration outperforms single-methodology analyses. In this Comment, we propose that use of next-generation 3D-oids that combine molecular, morphological and spatial information will promote tissue analyses and bring us closer to engineering functional organs.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Fachkommentar, Meinungsartikel
Schlagwörter Context (archaeology) ; Spatial Contextual Awareness ; Spatial Analysis ; Morphology (biology) ; Spatial Ecology
ISSN (print) / ISBN 1471-0072
e-ISSN 1471-0080
Zeitschrift Nature Reviews - Molecular Cell Biology
Verlag Nature Publishing Group
Verlagsort Heidelberger Platz 3, Berlin, 14197, Germany
Begutachtungsstatus Peer reviewed
Institut(e) Institute of AI for Health (AIH)
Institute of Computational Biology (ICB)