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Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.
Angew. Chem.-Int. Edit. 51, 432-435 (2012)
Membrane proteins in their native cellular membranes are accessible by dynamic nuclear polarization magic angle spinning solid-state NMR spectroscopy without the need of purification and reconstitution (see picture). Dynamic nuclear polarization is essential to achieve the required gain in sensitivity to observe the membrane protein of interest.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Membrane Proteins ; Nmr Spectroscopy ; Structural Biology ; Structure Elucidation; RESOLUTION
ISSN (print) / ISBN
1433-7851
e-ISSN
1521-3773
Zeitschrift
Angewandte Chemie - Internationale Edition
Quellenangaben
Band: 51,
Heft: 2,
Seiten: 432-435
Verlag
Wiley
Verlagsort
Weinheim
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Structural Biology (STB)