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Ma, R. ; Söntges, S. ; Shoham, S. ; Ntziachristos, V. ; Razansky, D.

Fast scanning coaxial optoacoustic microscopy.

Biomed. Opt. Express 3, 1724-1731 (2012)
Verlagsversion Volltext PMC
Open Access Gold
The hybrid nature of optoacoustic imaging might impose limitations on concurrent placement of optical and ultrasonic detection components, especially in high resolution microscopic applications that require dense arrangements and miniaturization of components. This hinders optimal deployment of the optical excitation and ultrasonic detection paths, leading to reduction of imaging speed and spatial resolution performance. We suggest a compact coaxial design for optoacoustic microscopy that allows optimizing both the light illumination and ultrasonic detection parameters of the imaging system. System performance is showcased in phantoms and in vivo imaging of microvasculature, achieving real time operation in two dimensions and penetration of 6 mm into optically dense human tissues.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter RESOLUTION PHOTOACOUSTIC MICROSCOPY; IN-VIVO; TOMOGRAPHY
ISSN (print) / ISBN 2156-7085
e-ISSN 2156-7085
Zeitschrift Biomedical Optics Express
Quellenangaben Band: 3, Heft: 7, Seiten: 1724-1731 Artikelnummer: , Supplement: ,
Verlag Optical Society of America (OSA)
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)