PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Mihaljevic, A.L.* ; Esposito, I. ; Michalski, C.W.* ; Kleeff, J.* ; Friess, H.*

Defining new pancreatic tumour entities by molecular analysis.

Pancreatol. 9, 334-339 (2009)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Recent advances in molecular biology, biochemistry and genetics have broadened our understanding of tumourigenesis and of the maintenance and spread of pancreatic cancer far beyond traditional microscopic histopathological analysis. While the main focus of pancreatic cancer research has been on pancreatic ductal adenocarcinoma, molecular research has also led to a better understanding of rare tumours of the pancreas, as well as to the definition of previously unknown tumour entities that can only be identified through the application of molecular tools. Furthermore, molecular analysis increasingly reveals the genetic and cell biological heterogeneity of established tumour entities, making sub-classification of tumours possible. Genetic and molecular approaches may, therefore, not only lead to a better understanding of the pathogenesis of pancreatic tumours, but also culminate in more precise diagnosis as well as individually tailored treatment strategies for affected patients.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
3.043
1.240
3
3
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Pancreatic cancer; Tumour entities; Molecular analysis; Mutation; mucinous cystic neoplasms; ras gene-mutations; intraepithelial neoplasia; aberrant methylation; immunohistochemical analysis; ductal adenocarcinoma; clinical-implications; precursor lesions; cell-carcinoma; p53 protein
Sprache englisch
Veröffentlichungsjahr 2009
HGF-Berichtsjahr 2009
ISSN (print) / ISBN 1424-3903
e-ISSN 1424-3911
Zeitschrift Pancreatology
Quellenangaben Band: 9, Heft: 4, Seiten: 334-339 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort BASEL
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Pathology (PATH)
POF Topic(s) 30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-500300-001
DOI 10.1159/000212081
Scopus ID 65649120817
PubMed ID 19451742
Erfassungsdatum 2009-12-31
[➜Korrektur melden]