PuSH - Publikationsserver des Helmholtz Zentrums München: Dynamic MR mammography : Multidimensional visualization of contrast enhancement in virtual reality.

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Hellwig, G. ; Englmeier, K.-H. ; Griebel, J.* ; Lucht, R.* ; Delorme, St.* ; Siebert, M. ; Brix, G.*

Dynamic MR mammography : Multidimensional visualization of contrast enhancement in virtual reality.

Radiologe 40, 262-266 (2002)

Open Access Gold möglich sobald Verlagsversion bei der ZB eingereicht worden ist.

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Background: The purpose of this study was the development of a method for fast and efficient analysis of dynamic MR images of the female breast. The image data sets were acquired with a saturation-recovery turbo-FLASH sequence which enables the detection of the kinetics of the contrast agent concentration in the whole breast with a high temporal and spatial resolution. In addition, a morphologic 3D-FLASH data set was acquired.Methods: The dynamic image datasets were analyzed by a pharmacokinetic model which enables the representation of the relevant functional tissue information by two parameters. In order to display simultaneously morphologic and functional tissue information, we developed a multidimensional visualization system, which enables a practical and intuitive human-computer interface in virtual reality.Discussions:The developed system allows the fast and efficient analysis of dynamic MR data sets. An important clinical application is the localization and definition of multiple lesions of the female breast.

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