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Wang, J.* ; Wu, W.* ; Henkelmann, B. ; You, L.* ; Kettrup, A. ; Schramm, K.-W.

Presence of estrogenic activity from emission of fossil fuel combustion as detected by a recombinant yeast bioassay.

Atmos. Environ. 37, 3225-3235 (2003)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Estrogenic activities of emission samples generated by fossil fuel combustion were investigated with human estrogen receptor (ER) recombinant yeast bioassay. The results showed that there were weak but clear estrogenic activities in combustion emissions of fossil fuels including coal, petroleum, and diesel. The estrogenic relative potency (RP) of fossil fuel combustion was the highest in petroleum-fired car, followed by coal-fired stove, diesel-fired agrimotor, coal-fired electric power station. On the other hand, the estrogenic relative inductive efficiency (RIE) was the highest in coal-fired stove and coal-fired electric power station, followed by petroleum-fired car and diesel-fired agrimotor. The estrogenic activities in the sub-fractions from chromatographic separation of emitted materials were also determined. The results indicated that different chemical fractions in these complex systems have different estrogenic potencies. The GC/MS analysis of the emission showed that there were many aromatic carbonyls, big molecular alcohol, PAHs and derivatives, and substituted phenolic compounds and derivatives which have been reported as environmental estrogens. The existence of estrogenic substances in fossil fuel combustion demands further investigation of their potential adverse effects on human and on the ecosystem. The magnitude of pollution due to global usage of fossil fuels makes it imperative to understand the issue of fossil fuel-derived endocrine activities and the associated health risks, particularly the aggregated risks stemmed from exposure to toxicants of multiple sources.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Fossil fuel; Emission; Estrogenic activity; Yeast bioassay
ISSN (print) / ISBN 1352-2310
e-ISSN 1873-2844
Zeitschrift Atmospheric Environment
Quellenangaben Band: 37, Heft: 23, Seiten: 3225-3235 Artikelnummer: , Supplement: ,
Verlag Elsevier
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Ecological Chemistry (IOEC)