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Tetko, I.V.

Associative Neural Network.

Methods Mol. Biol. 458, 187-204 (2008)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
An associative neural network (ASNN) is an ensemble-based method inspired by the function and structure of neural network correlations in brain. The method operates by simulating the short- and long-term memory of neural networks. The long-term memory is represented by ensemble of neural network weights, while the short-term memory is stored as a pool of internal neural network representations of the input pattern. The organization allows the ASNN to incorporate new data cases in short-term memory and provides high generalization ability without the need to retrain the neural network weights. The method can be used to estimate a bias and the applicability domain of models. Applications of the ASNN in QSAR and drug design are exemplified.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Herausgeber Livingstone, D.S.*
Schlagwörter ensemble networks; memory; drug design; LIBRARY mode
ISSN (print) / ISBN 1064-3745
e-ISSN 1940-6029
Konferenztitel Artitificial Neural Networks: Methods and Applications
Zeitschrift Methods in Molecular Biology
Quellenangaben Band: 458, Heft: , Seiten: 187-204 Artikelnummer: , Supplement: ,
Reihe Methods in Molecular Biology
Verlag Springer
Verlagsort Berlin [u.a.]
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Bioinformatics and Systems Biology (IBIS)