Fluorescence Molecular Tomography using a-priori Photoacoustic data.
    
    
        
    
    
        
        Proc. SPIE 6856:685617 (2008)
    
    
		
		
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			Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
		
     
    
		
		
			
				We present the first hybrid photoacoustic fluorescence molecular tomography system, capable of three-dimensional imaging of both fluorochrome and chromophore distributions in highly scattering and absorbing tissue. Quantitative three-dimensional maps of optical absorption coefficient are acquired using photoacoustic tomography. The reconstructed absorption data is fed into the Fluorescence Molecular Tomography inversion scheme in order to improve its accuracy and quatification capabilities in the presence of strong and distributed absorbers that are expected to bias stand-alone fluorescence reconstructions. At all, having both techniques in one hybrid modality yields a system that combines high molecular specificity and targeting flexibility of fluorescent imaging and high spatial resolution functional information obtained via photo-acoustic images.
			
			
				
			
		 
		
			
				
					
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
    
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        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2008
    
 
    
        Prepublished im Jahr 
        
    
 
    
        HGF-Berichtsjahr
        0
    
 
    
    
        ISSN (print) / ISBN
        0277-786X
    
 
    
        e-ISSN
        1996-756X
    
 
    
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        Konferenztitel
        Photons Plus Ultrasound: Imaging and Sensing 2008: The Ninth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acoust
    
 
	
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	    Band: 6856,  
	    Heft: ,  
	    Seiten: ,  
	    Artikelnummer: 685617 
	    Supplement: ,  
	
    
 
  
        
            Reihe
            Proceedings of SPIE
        
 
        
            Verlag
            SPIE
        
 
        
            Verlagsort
            Bellingham, WA
        
 
	
        
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        Begutachtungsstatus
        Peer reviewed
    
 
     
    
        POF Topic(s)
        30205 - Bioengineering and Digital Health
    
 
    
        Forschungsfeld(er)
        Enabling and Novel Technologies
    
 
    
        PSP-Element(e)
        G-505500-001
    
 
    
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        Erfassungsdatum
        2008-12-31