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Wambersie, A.* ; Menzel, H.G.* ; Gahbauer, R.A.* ; Jones, D.T.* ; Michael, B.D.* ; Paretzke, H.G.

Biological Weighting of Absorbed Dose in Radiation Therapy.

Radiat. Prot. Dosim. 99, 445-452 (2002)
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Absorbed dose is a quantity which is scientifically rigorously defined and used to quantify the exposure of biological objects, including humans. to ionising radiation. There is. however. no unique relationship between absorbed dose and induced biological effects. The effects induced by a given absorbed dose to a given biological object depend also oil radiation quality and temporal distribution of the irradiation. In radiation therapy, empirical approaches are still used today to account for these dependencies in practice. In hadron therapy (neutrons, protons. ions). radiation quality is accounted for with a diversity of (almost hospital specific) methods. The necessity to account for temporal aspects is well known in external beam therapy and in high dose rate brachytherapy, The paper reviews the approaches for weighting the absorbed dose in radiation therapy, and focusses on the clinical aspects of these approaches, in particular the accuracy requirements.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter NEUTRON THERAPY; RADIOBIOLOGICAL EFFECTIVENESS; SPECIFICATION; QUALITY; BEAMS; RBE
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Quellenangaben Band: 99, Heft: , Seiten: 445-452 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Verlagsort Oxford
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed