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Taverna, E.* ; Götz, M. ; Huttner, A.B.*

The cell biology of neurogenesis: Toward an understanding of the development and evolution of the neocortex.

Annu. Rev. Cell Dev. Biol. 30, 465-502 (2014)
DOI
Neural stem and progenitor cells have a central role in the development and evolution of the mammalian neocortex. In this review, we first provide a set of criteria to classify the various types of cortical stem and progenitor cells. We then discuss the issue of cell polarity, as well as specific subcellular features of these cells that are relevant for their modes of division and daughter cell fate. In addition, cortical stem and progenitor cell behavior is placed into a tissue context, with consideration of extracellular signals and cell-cell interactions. Finally, the differences across species regarding cortical stem and progenitor cells are dissected to gain insight into key developmental and evolutionary mechanisms underlying neocortex expansion.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Neural Stem Cells ; Neural Progenitors ; Radial Glia ; Cilium ; Neuroepithelial Cells ; Apical And Basal Processes ; Cell Biology ; Neocortex Evolution ; Cell Polarity ; Asymmetric Cell Division ; Interkinetic Nuclear Migration ; Inm ; Cell Cycle ; Cell Fate Determination; Interkinetic Nuclear Migration; Radial Glial-cells; Neural Stem-cells; Cerebral Cortical Development; Extracellular Membrane-particles; Outer Subventricular Zone; Apical Plasma-membrane; Central-nervous-system; Developing Mouse Neocortex; Pax6 Transcription Factor
ISSN (print) / ISBN 1081-0706
e-ISSN 1530-8995
Zeitschrift Annual Review of Cell and Developmental Biology
Quellenangaben Band: 30, Heft: , Seiten: 465-502 Artikelnummer: , Supplement: ,
Verlag Annual Reviews
Verlagsort Palo Alto, Calif.
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Stem Cell Research (ISF)