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Viral hepatitis: The bumpy road to animal models for HBV infection.
Nat. Rev. Gastroenterol. Hepatol. 14, 327-328 (2017)
Cell culture infection models help to develop antiviral agents, but animal models are required to understand complex virus-host interactions and the development of immune therapies. Although identification of the HBV uptake receptor enabled establishing cell lines that replicate HBV from its natural transcription template, animal models supporting the full HBV life cycle are still lacking.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Hepatitis-b-virus; Mice; Replication; Leads
ISSN (print) / ISBN
1759-5045
e-ISSN
1759-5053
Zeitschrift
Nature Reviews - Gastroenterology & Hepatology
Quellenangaben
Band: 14,
Heft: 6,
Seiten: 327-328
Verlag
Nature Publishing Group
Verlagsort
New York
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Virology (VIRO)