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Glial control of neurogenesis.

Curr. Opin. Neurobiol. 47, 188-195 (2017)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Glial cells are central components of all neurogenic niches in the embryonic as well as in the adult central nervous system. While neural stem cells (NSCs) themselves exhibit glial features the behavior of NSCs is also strongly influenced by niche glial cells. Recently, studies have begun to uncover a large variety of glial cell-extrinsic as well as intrinsic factors that play crucial roles in the control of NSCs and the regulation of the cellular output from the neurogenic niches. In this review, we focus on mechanisms underlying the formation of adult NSCs by embryonic radial glia cells, discuss the influence of niche glia cells on adult NSCs and examine how the neurogenic potential of glial cells is controlled.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Neural Stem-cells; Adult Hippocampal Neurogenesis; In-vitro; Subventricular Zone; Subependymal Zone; Embryonic Origin; Reactive Gliosis; Ependymal Cells; Olfactory-bulb; Injured Brain
ISSN (print) / ISBN 0959-4388
e-ISSN 1873-6882
Quellenangaben Band: 47, Heft: , Seiten: 188-195 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort London
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed