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Afghani, J. ; Traidl-Hoffmann, C. ; Schmitt-Kopplin, P. ; Reiger, M. ; Müller, C.

An overview of the latest metabolomics studies on atopic eczema with new directions for study.

Int. J. Mol. Sci. 23:8791 (2022)
Verlagsversion DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Atopic eczema (AE) is an inflammatory skin disorder affecting approximately 20% of children worldwide and early onset can lead to asthma and allergies. Currently, the mechanisms of the disease are not fully understood. Metabolomics, the analysis of small molecules in the skin produced by the host and microbes, opens a window to observe the mechanisms of the disease which then may lead to new drug targets for AE treatment. Here, we review the latest advances in AE metabolomics, highlighting both the lipid and non-lipid molecules, along with reviewing the metabolites currently known to reside in the skin.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Atopic Eczema ; Atopic Dermatitis ; Dermatitis ; Metabolomics ; Skin ; Lipidomics
ISSN (print) / ISBN 1422-0067
e-ISSN 1661-6596
Zeitschrift International Journal of Molecular Sciences
Quellenangaben Band: 23, Heft: 15, Seiten: , Artikelnummer: 8791 Supplement: ,
Verlag MDPI
Verlagsort Basel
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Research Unit BioGeoChemistry and Analytics (BGC)
Institute of Environmental Medicine (IEM)
Förderungen Center for Allergy Research and Education
Helmholtz Association
International Visegrad Fund
Christine Kühne – Center for Allergy Research and Education