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Native ChIP: Studying the genome-wide distribution of histone modifications in cells and tissue.

In: Chromatin Immunoprecipitation. Berlin [u.a.]: Springer, 2024. 1-16 (Methods Mol. Biol. ; 2846)
DOI PMC
For the genome-wide mapping of histone modifications, chromatin immunoprecipitation (ChIP) followed by high-throughput sequencing remains the benchmark method. While crosslinked ChIP can be used for all kinds of targets, native ChIP is predominantly used for strong and direct DNA interactors like histones and their modifications. Here we describe a native ChIP protocol that can be used for cells and tissue material.
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Publikationstyp Artikel: Sammelbandbeitrag/Buchkapitel
Korrespondenzautor
Schlagwörter Chip-seq ; Chromatin Immunoprecipitation (chip) ; Histone Modifications ; Native Protein-dna Interactions
ISSN (print) / ISBN 1064-3745
e-ISSN 1940-6029
Bandtitel Chromatin Immunoprecipitation
Quellenangaben Band: 2846, Heft: , Seiten: 1-16 Artikelnummer: , Supplement: ,
Verlag Springer
Verlagsort Berlin [u.a.]
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed