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1.
Gu, W.* et al.: IRP1 deficiency alters mitochondrial metabolism and protects against metabolic syndrome pathologies. JCI insight 11:e183247 (2026)
2.
Tesfaigzi, Y.* et al.: New approaches to uncover COPD pathobiology and develop therapies. JCI insight 11:e199693 (2026)
3.
Koc-Gunel, S.* et al.: Targeting fibroblast-endothelial interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics. JCI insight 10:e187899 (2025)
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Rüeger, S.* et al.: Early treatment and PD1 inhibition enhance HIV-specific functionality of follicular CD8+ T cells. JCI insight 10:e180309 (2025)
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Wittenzellner, K.* et al.: Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time. JCI insight 10:e169105 (2025)
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Burgy, O.* et al.: Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis. JCI insight 9:e168889 (2024)
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Sui, J.* et al.: Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD. JCI insight 9:e180239 (2024)
8.
Bajwa, P.* et al.: Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis. JCI insight 8:17 (2023)
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Khajavi, N.* et al.: TRPM7 kinase is required for insulin production and compensatory islet responses during obesity. JCI insight 8:e163397 (2023)
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Rohwedder, I.* et al.: A20 and the non-canonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny. JCI insight 8:e155968 (2023)
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Wang, Q. et al.: Metabolic heterogeneity in adrenocortical carcinoma impacts patient outcomes. JCI insight 8:18 (2023)
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Buck, A. ; Prade, V.M. ; Kunzke, T. ; Erben, R.G.* & Walch, A.K.: Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice. JCI insight 7:e162138 (2022)
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Hong, L.* et al.: Prdm6 controls heart development by regulating neural crest cell differentiation and migration. JCI insight 7:e156046 (2022)
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Kullmann, S. et al.: Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. JCI insight 7:e161498 (2022)
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Li, Y.* et al.: Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. JCI insight 7:e157035 (2022)
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Modak, M.* et al.: CD206+ tumor-associated macrophages cross-present tumor antigen and drive anti-tumor immunity. JCI insight 7:e155022 (2022)
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Dietz, B.* et al.: Detection of diabetes from whole-body MRI using deep learning. JCI insight 6:e146999 (2021)
18.
Kaiser, R.* et al.: Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI insight 6:e150862 (2021)
19.
Willmes, D.M. et al.: The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms. JCI insight 6:e136083 (2021)
20.
Belle, J.I.* et al.: MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction. JCI insight 5:e125690 (2020)
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