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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Challenges of translating genetic tests into clinical and public health practice.
Nat. Rev. Genet. 10, 489-495 (2009)
Research in genetics and genomics has led to an expanding list of molecular genetic tests, which are increasingly entering health care systems. However, the evidence surrounding the benefits and harms of these tests is frequently weak. Here we present the main challenges to the successful translation of new research findings about genotype-phenotype associations into clinical practice. We discuss the means to achieve an accelerated translation research agenda that is conducted in a reasonable, fair and efficient manner.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
egapp working group; cost-effectiveness; technology-assessment; reducing morbidity; colorectal-cancer; lynch syndrome; services; care; strategies; disorders
ISSN (print) / ISBN
1471-0056
e-ISSN
1471-0064
Zeitschrift
Nature Reviews - Genetics
Quellenangaben
Band: 10,
Heft: 7,
Seiten: 489-495
Verlag
Nature Publishing Group
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed