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Open Access Green as soon as Postprint is submitted to ZB.
Challenges of translating genetic tests into clinical and public health practice.
Nat. Rev. Genet. 10, 489-495 (2009)
Research in genetics and genomics has led to an expanding list of molecular genetic tests, which are increasingly entering health care systems. However, the evidence surrounding the benefits and harms of these tests is frequently weak. Here we present the main challenges to the successful translation of new research findings about genotype-phenotype associations into clinical practice. We discuss the means to achieve an accelerated translation research agenda that is conducted in a reasonable, fair and efficient manner.
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Publication type
Article: Journal article
Document type
Review
Keywords
egapp working group; cost-effectiveness; technology-assessment; reducing morbidity; colorectal-cancer; lynch syndrome; services; care; strategies; disorders
ISSN (print) / ISBN
1471-0056
e-ISSN
1471-0064
Journal
Nature Reviews - Genetics
Quellenangaben
Volume: 10,
Issue: 7,
Pages: 489-495
Publisher
Nature Publishing Group
Non-patent literature
Publications
Reviewing status
Peer reviewed