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Loewenstein, Y.* ; Raimondo, D.* ; Redfern, O.C.* ; Watson, J.* ; Frishman, D. ; Linial, M.* ; Orengo, C.* ; Thornton, J.* ; Tramontano, A.*

Protein function annotation by homology-based inference.

Genome Biol. 10:207 (2009)
Verlagsversion Volltext DOI PMC
Open Access Gold
With many genomes now sequenced, computational annotation methods to characterize genes and proteins from their sequence are increasingly important. The BioSapiens Network has developed tools to address all stages of this process, and here we review progress in the automated prediction of protein function based on protein sequence and structure.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter structure allignment; domain interactions; interacting proteins; hierarchical-classification; evolutionary conservation; structural genomics; 3D structure; database; prediction; sites
ISSN (print) / ISBN 1474-760X
e-ISSN 1465-6906
Zeitschrift Genome Biology
Quellenangaben Band: 10, Heft: 2, Seiten: , Artikelnummer: 207 Supplement: ,
Verlag BioMed Central
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Bioinformatics and Systems Biology (IBIS)