Filippini, T.* ; Michalke, B. ; Wise, L.A.* ; Malagoli, C.* ; Malavolti, M.* ; Vescovi, L.* ; Salvia, C.* ; Bargellini, A.* ; Sieri, S.* ; Krogh, V.* ; Ferrante, M.* ; Vinceti, M.*
Diet composition and serum levels of selenium species: A cross-sectional study.
Food Chem. Toxicol. 115, 482-490 (2018)
Selenium is a trace element of both nutritional and toxicological interest, depending on its dose and chemical form. Diet is the primary source of exposure for most individuals. We sought to investigate the influence of food intake on serum levels of selenium species. Among fifty subjects randomly selected from a Northern Italian population, we assessed dietary habits using a validated semi-quantitative food frequency questionnaire. We also measured circulating levels of selenium species in serum using high pressure liquid chromatography associated with inductively-coupled plasma dynamic reaction cell mass spectrometer. Circulating levels of inorganic selenium, the most toxic selenium species, were positively associated with intake of fish, legumes and dry fruits, and inversely associated with intake of dairy products and mushrooms. Concerning the organic selenium species, selenoproteinP-bound selenium was inversely associated with intake of fish, fresh fruits, vegetables, and legumes, while selenocysteine-bound selenium positively associated with intake of fresh fruit, potato, legume and mushroom. In the present study, intakes of different foods were correlated with different types of selenium species. These results have important public health implications when assessing the nutritional and toxicological potential of diet composition with reference to selenium exposure.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Typ der Hochschulschrift
Herausgeber
Schlagwörter
Selenium ; Dietary Intake ; Food ; Speciation Analysis ; Toxicological Profile ; Cross-sectional Study; Polycyclic Aromatic-hydrocarbons; Lung Epithelial-cells; Yangtze-river Delta; 6 European Cities; Ambient Air; Oxidative Stress; Mouse Lung; A549 Cells; Cytotoxic Responses; Seasonal-variation
Keywords plus
Sprache
Veröffentlichungsjahr
2018
Prepublished im Jahr
HGF-Berichtsjahr
2018
ISSN (print) / ISBN
0278-6915
e-ISSN
0278-6915
ISBN
Bandtitel
Konferenztitel
Konferzenzdatum
Konferenzort
Konferenzband
Quellenangaben
Band: 115,
Heft: ,
Seiten: 482-490
Artikelnummer: ,
Supplement: ,
Reihe
Verlag
Elsevier
Verlagsort
Po Box 211, 1000 Ae Amsterdam, Netherlands
Tag d. mündl. Prüfung
0000-00-00
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Gutachter
Prüfer
Topic
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Veröffentlichungsdatum
0000-00-00
Anmeldedatum
0000-00-00
Anmelder/Inhaber
weitere Inhaber
Anmeldeland
Priorität
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30202 - Environmental Health
Forschungsfeld(er)
Environmental Sciences
PSP-Element(e)
G-504800-002
Förderungen
Copyright
Erfassungsdatum
2018-06-20