Startseite
English
Erweiterte Suche
Durchblättern nach ...
Publikationen im Überblick
Ansprechpartner
Hilfe
Verlagsversion
DOI
PMC
 |
Free by publisher |
|
möglich sobald bei der ZB eingereicht worden ist.
Catching lipid droplet contacts by proteomics.
Contact 2, DOI: 10.1177/2515256419859186 (2019)
Lipid droplets (LDs), important organelles for energy storage and involved in the development of metabolic disorders, are extremely dynamic and interact with many other cellular compartments to orchestrate lipid metabolism. Little is known about how these organelle contacts are changed according to cellular needs and functions under different metabolic and pathological conditions and which proteins regulate this. Here, we summarize recent exciting discoveries about the reorganization of organelle contacts in steatotic liver, including the identification of novel LD contact site proteins in cell lines and in animals. We also discuss state of the art proteomics workflows that enable the characterization of LD-organelle contacts and tethering proteins and give an outlook how this can inform obesity research.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten
[➜Einloggen]
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Contact Site ; Lipid Droplet ; Nonalcoholic Fatty Liver Disease ; Phosphoproteome ; Proteomics ; Steatosis
ISSN (print) / ISBN
2515-2564
e-ISSN
2515-2564
Zeitschrift
Contact
Quellenangaben
Band: 2
Verlag
Sage
Verlagsort
London
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Diabetes and Obesity (IDO)