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Bocchi, R. ; Götz, M.

Neuronal reprogramming for brain repair: Challenges and perspectives.

Trends Mol. Med. 26, 890-892 (2020)
Postprint DOI PMC
Open Access Green
Brain injuries and neurodegenerative diseases elicit neuronal loss that persists because the adult mammalian brain lacks robust regenerative abilities. Direct reprogramming of local glial cells into neurons is a promising strategy for neuronal replacement in vivo. We discuss recent advances and future challenges in this approach to brain repair.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Korrespondenzautor
Schlagwörter Astrocytes ; Brain Repair ; Neuronal Loss ; Neuronal Reprogramming; Conversion; Disease; Glia
ISSN (print) / ISBN 1471-4914
e-ISSN 1471-499X
Zeitschrift Trends in Molecular Medicine
Quellenangaben Band: 26, Heft: 10, Seiten: 890-892 Artikelnummer: , Supplement: ,
Verlag Elsevier
Verlagsort The Boulevard, Langford Lane, Kidlington, Oxford Ox5 1gb, Oxon, England
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Stem Cell Research (ISF)
Förderungen SyNergy Excellence Cluster
Swiss National Science Foundation (SNSF) post-doctoral fellowship
European Research Council (ERC) grant ChroNeuroRepair
Roger de Spoelberch Foundation
Micronet (Era-Net)
German Research Foundation