Despite major advances in artificial intelligence (AI) research for healthcare, the deployment and adoption of AI technologies remain limited in clinical practice. This paper describes the FUTURE-AI framework, which provides guidance for the development and deployment of trustworthy AI tools in healthcare. The FUTURE-AI Consortium was founded in 2021 and comprises 117 interdisciplinary experts from 50 countries representing all continents, including AI scientists, clinical researchers, biomedical ethicists, and social scientists. Over a two year period, the FUTURE-AI guideline was established through consensus based on six guiding principles-fairness, universality, traceability, usability, robustness, and explainability. To operationalise trustworthy AI in healthcare, a set of 30 best practices were defined, addressing technical, clinical, socioethical, and legal dimensions. The recommendations cover the entire lifecycle of healthcare AI, from design, development, and validation to regulation, deployment, and monitoring.
Institut(e)Institute for Machine Learning in Biomed Imaging (IML)
FörderungenEuropean Research Council Royal Academy of Engineering, Hospital Clinic Barcelona Carnegie Cooperation New York, Human frontier science programme Natural Sciences and Engineering Research Council of Canada (NSERC) Australian National Health and Medical Research Council United States Department of Defence Korean government A*STAR Career Development Award Agency for Science, Technology and Research (A*STAR) European Union's Horizon Europe European Union National Institute for Health and Care Research Barts Biomedical Research Centre Infraestructura de Medicina de Precisin asociada a la Ciencia y la Tecnologia - Instituto de Salud Carlos III Fondo Europeo de Desarrollo Regional (FEDER) Cancer Research UK programme National Institute of Biomedical Imaging and Bioengineering (NIBIB) of the National Institutes of Health AIMED Ministry of Science, Innovation and Universities of the Government of Spain European Research Council (ERC) Horizon Europe - Pillar II Wellcome Flagship Programme Google Research, Independent Research Fund Denmark Netherlands Organisation for Scientific Research (NWO) Ministry of Science, Technology and Innovation of Colombia Gordon and Betty Moore Foundation Google Award for Inclusion Research, Fraunhofer Heinrich Hertz Institute, US National Institutes of Health, National Council for Scientific and Technological Development (CNPq) European Heart Network NIBIB/University of Chicago (MIDRC) , Hong Kong Research Grants Council Theme-based Research Scheme Ministry of High Education of Tunisia Fogarty International Center of the National Institutes of Health Natural Science Foundation of China Israel Science Foundation National Institutes of Health (NIH) Dutch Cancer Society (KWF Kankerbestrijding) U.S. Department of Defense (DOD)