Das, A. ; Karg, E.* ; Ferron, G.A.* ; Schnelle-Kreis, J. ; Mandariya, A.K.* ; Habib, G.* ; Wiedensohler, A.* ; Pöhlker, M.L.* ; Zimmermann, R. ; Ahlawat, A.*
     
 
    
        
Increased particle mass deposition on lung tissue due to industrial and waste-burning activities.
    
    
        
    
    
        
        Environ. Int. 201:109548 (2025)
    
    
    
		
		
			
				Understanding airborne particle mass deposition in the lungs is crucial for assessing health effects, particularly in regions with severe air pollution. While several studies have modelled lung deposition, there is limited information on lung tissue deposition that incorporates factors like hygroscopicity and density in polluted environments or source-specific exposures. This study examines the impact of atmospheric aerosol properties, including particle number size distribution, effective density, and hygroscopic growth, on lung tissue deposition using data from a measurement campaign in Delhi, India. Using the Hygroscopic Particle Lung Deposition (HPLD) model, the number (TDn) and mass (TDm) of tissue-deposited particles were calculated for various episodes: biomass burning (BB), chloride (Cl), hydrocarbon-like organic aerosol (HOA), and relatively clean (RC) periods. Chloride episodes, linked to industrial and waste burning activities, showed the highest tissue deposition mass (28 pg cm-2h-1), followed by BB (22 pg cm-2h-1), HOA (17 pg cm-2h-1), and RC (14 pg cm-2h-1) on total inner lung surface area. In addition, incorporating hygroscopicity and density increased deposition estimates by 1.8-2.8 times. This study underscores the importance of quantifying tissue deposition doses for improving exposure assessments, particularly in highly polluted regions where elevated particulate levels exacerbate lung inflammation, respiratory issues, and cancer risk.
			
			
				
			
		 
		
			
				
					
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        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
    
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        Schlagwörter
        Atmospheric Aerosol Particles ; Density ; Hygroscopicity ; Lung Deposition ; Tissue Deposition Dose; Aerosol Optical-properties; Respiratory-tract; Hygroscopic Growth; Relative-humidity; Effective Density; Chemical-composition; Mixing State; Size; Submicrometer; Model
    
 
    
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        englisch
    
 
    
        Veröffentlichungsjahr
        2025
    
 
    
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        0
    
 
    
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        2025
    
 
    
    
        ISSN (print) / ISBN
        0160-4120
    
 
    
        e-ISSN
        1873-6750
    
 
    
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	    Band: 201,  
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	    Seiten: ,  
	    Artikelnummer: 109548 
	    Supplement: ,  
	
    
 
  
        
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            Verlag
            Elsevier
        
 
        
            Verlagsort
            The Boulevard, Langford Lane, Kidlington, Oxford Ox5 1gb, England
        
 
	
        
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        Begutachtungsstatus
        Peer reviewed
    
 
     
    
        POF Topic(s)
        30202 - Environmental Health
    
 
    
        Forschungsfeld(er)
        Environmental Sciences
    
 
    
        PSP-Element(e)
        G-504500-001
    
 
    
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        Erfassungsdatum
        2025-06-16