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Das, A. ; Karg, E.* ; Ferron, G.A.* ; Schnelle-Kreis, J. ; Mandariya, A.K.* ; Habib, G.* ; Wiedensohler, A.* ; Pöhlker, M.L.* ; Zimmermann, R. ; Ahlawat, A.*

Increased particle mass deposition on lung tissue due to industrial and waste-burning activities.

Environ. Int. 201:109548 (2025)
Verlagsversion Forschungsdaten DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Understanding airborne particle mass deposition in the lungs is crucial for assessing health effects, particularly in regions with severe air pollution. While several studies have modelled lung deposition, there is limited information on lung tissue deposition that incorporates factors like hygroscopicity and density in polluted environments or source-specific exposures. This study examines the impact of atmospheric aerosol properties, including particle number size distribution, effective density, and hygroscopic growth, on lung tissue deposition using data from a measurement campaign in Delhi, India. Using the Hygroscopic Particle Lung Deposition (HPLD) model, the number (TDn) and mass (TDm) of tissue-deposited particles were calculated for various episodes: biomass burning (BB), chloride (Cl), hydrocarbon-like organic aerosol (HOA), and relatively clean (RC) periods. Chloride episodes, linked to industrial and waste burning activities, showed the highest tissue deposition mass (28 pg cm-2h-1), followed by BB (22 pg cm-2h-1), HOA (17 pg cm-2h-1), and RC (14 pg cm-2h-1) on total inner lung surface area. In addition, incorporating hygroscopicity and density increased deposition estimates by 1.8-2.8 times. This study underscores the importance of quantifying tissue deposition doses for improving exposure assessments, particularly in highly polluted regions where elevated particulate levels exacerbate lung inflammation, respiratory issues, and cancer risk.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Atmospheric Aerosol Particles ; Density ; Hygroscopicity ; Lung Deposition ; Tissue Deposition Dose; Aerosol Optical-properties; Respiratory-tract; Hygroscopic Growth; Relative-humidity; Effective Density; Chemical-composition; Mixing State; Size; Submicrometer; Model
Sprache englisch
Veröffentlichungsjahr 2025
HGF-Berichtsjahr 2025
ISSN (print) / ISBN 0160-4120
e-ISSN 1873-6750
Quellenangaben Band: 201, Heft: , Seiten: , Artikelnummer: 109548 Supplement: ,
Verlag Elsevier
Verlagsort The Boulevard, Langford Lane, Kidlington, Oxford Ox5 1gb, England
Begutachtungsstatus Peer reviewed
POF Topic(s) 30202 - Environmental Health
Forschungsfeld(er) Environmental Sciences
PSP-Element(e) G-504500-001
Scopus ID 105007442840
PubMed ID 40482623
Erfassungsdatum 2025-06-16