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Incident coronary heart disease, residual risk and traditional cardiovascular risk factors in the community: The role of the lipid-inflammatory axis.
Am. J. Prev. Cardiol.:101812 (2026)
Background and aims: Coronary heart disease (CHD) occurs even in individuals classified as “low-risk” by traditional cardiovascular risk factors (CVRFs). We aimed to investigate whether the combinations of high-sensitivity C-reactive protein (hsCRP), lipoprotein (a) (Lp(a)), or triglycerides (TGs) would modulate relative and absolute CHD risk within a low-risk population. Methods: A total of 63,740 individuals free of CHD at baseline were included. Participants were stratified according to CVRF burden at baseline: 0/1 vs. ≥2 CVRFs. Biomarkers were analyzed dichotomously: hsCRP (
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Coronary Heart Disease ; Residual Risk ; Risk Factor ; Atherosclerotic Cardiovascular Disease ; Framingham Risk Score ; Disease ; Absolute Risk Reduction ; Risk Assessment
ISSN (print) / ISBN
2666-6677
e-ISSN
2666-6677
Zeitschrift
American Journal of Preventive Cardiology
Quellenangaben
Artikelnummer: 101812
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)