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Schramm, K.-W. ; Klimm, C. ; Hofmaier, A.* ; Kettrup, A.

Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials.

Chemosphere 42, 551-557 (2001)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro. Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially. The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Bioassay; In vitro; Dioxin-like-response (DLR); Ah-receptor; EROD; P4501A1; PBT; PCDD/F; PAH; PHAH; Emission; Ashes
ISSN (print) / ISBN 0045-6535
e-ISSN 1879-1298
Journal Chemosphere
Quellenangaben Volume: 42 , Issue: 5-7, Pages: 551-557 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Kidlington, Oxford
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Ecological Chemistry (IOEC)