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Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials.
Chemosphere 42, 551-557 (2001)
Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro. Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially. The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Bioassay; In vitro; Dioxin-like-response (DLR); Ah-receptor; EROD; P4501A1; PBT; PCDD/F; PAH; PHAH; Emission; Ashes
ISSN (print) / ISBN
0045-6535
e-ISSN
1879-1298
Journal
Chemosphere
Quellenangaben
Volume: 42 ,
Issue: 5-7,
Pages: 551-557
Publisher
Elsevier
Publishing Place
Kidlington, Oxford
Reviewing status
Peer reviewed
Institute(s)
Institute of Ecological Chemistry (IOEC)