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Schramm, K.-W. ; Klimm, C. ; Hofmaier, A.* ; Kettrup, A.

Comparison of dioxin-like-response in vitro and chemical analysis of emissions and materials.

Chemosphere 42, 551-557 (2001)
DOI PMC
Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Samples from industrial and domestic emissions and materials were investigated by using in vitro assays for dioxin-like-response (DLR) and chemical analysis. The results show a small part of persistent bioaccumulative toxicants (PBT) to be responsive in vitro. Clean-up procedures directed to persistence decrease the amount of inducing toxicants substantially. The comparison of biological in vitro (B) and chemical (A) analysis show ratios between B and A below 10 for DLR of persistent inductors. The consideration of PAH improved the knowledge about unknown less persistent agonists.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Bioassay; In vitro; Dioxin-like-response (DLR); Ah-receptor; EROD; P4501A1; PBT; PCDD/F; PAH; PHAH; Emission; Ashes
ISSN (print) / ISBN 0045-6535
e-ISSN 1879-1298
Journal Chemosphere
Quellenangaben Volume: 42 , Issue: 5-7, Pages: 551-557 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Kidlington, Oxford
Reviewing status Peer reviewed
Institute(s) Institute of Ecological Chemistry (IOEC)