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Guan, M.* ; Marschall, S. ; Raspa, M.* ; Pickard, A.R.* ; Fray, M.D.*

Overview of new developments in and the future of cryopreservation in the laboratory mouse.

Mamm. Genome 23, 572-579 (2012)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
The large-scale mutagenesis programmes underway around the world are generating thousands of novel GA mouse strains that need to be securely archived. In parallel with advances in mutagenesis, the procedures used to cryopreserve mouse stocks are being continually refined in order to keep pace with demand. Moreover, the construction of extensive research infrastructures for systematic phenotyping is fuelling demand for these novel strains of mice and new approaches to the distribution of frozen and unfrozen embryos and gametes are being developed in order to reduce the dependency on the transportation of live mice. This article highlights some contemporary techniques used to archive, rederive, and transport mouse strains around the world.
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Publication type Article: Journal article
Document type Scientific Article
Keywords IN-VITRO FERTILIZATION; METHYL-BETA-CYCLODEXTRIN; OVARIAN TISSUE; ZONA-PELLUCIDA; TRANSGENIC MOUSE; HEPATITIS-VIRUS; LIVE BIRTHS; DEGREES-C; SPERM; SPERMATOZOA
Language english
Publication Year 2012
HGF-reported in Year 2012
ISSN (print) / ISBN 0938-8990
e-ISSN 1432-1777
Quellenangaben Volume: 23, Issue: 9-10, Pages: 572-579 Article Number: , Supplement: ,
Publisher Springer
Reviewing status Peer reviewed
POF-Topic(s) 30201 - Metabolic Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-500600-003
PubMed ID 22936001
Scopus ID 84867300572
Erfassungsdatum 2012-11-15