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Dean-Ben, X.L. ; Ntziachristos, V. ; Razansky, D.

Artefact reduction in optoacoustic tomographic imaging by estimating the distribution of acoustic scatterers.

J. Biomed. Opt. 17:110504 (2012)

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ABSTRACT. The quality of optoacoustic tomographic reconstructions can be severely affected by acoustic reflections or scattering arising at interfaces of highly mismatched organs, such as bones, lungs, or other air-containing cavities. We present a procedure to reduce the associated artefacts based on estimation of the acoustic scatterers distribution within the imaged object. Signals generated by a strong optical absorber are processed and used in a weighted back-projection algorithm. Experimental results in a tissue-mimicking phantom clearly demonstrate improved performance as compared to the case in which no information on the distribution of acoustic scatterers is available.

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