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Non-invasive carotid imaging using optoacoustic tomography.
Opt. Express. 20, 25044-25057 (2012)
The high prevalence of atherosclerosis and the corresponding derived morbidity drives the investigation of novel imaging tools for disease diagnosis and assessment. Multi-spectral optoacoustic tomography (MSOT) can resolve structural, hemodynamic and molecular parameters that relate to cardiovascular disease. Similarly to ultrasound imaging, optoacoustic (photoacoustic) imaging can be implemented as a handheld arrangement which further brings dissemination potential to point of care applications. Correspondingly, we experimentally investigate herein the performance of non-invasive optoacoustic scanning developed for carotid imaging, in phantoms and humans. The results demonstrate that traditional transducers employed in ultrasound imaging do not offer optimal MSOT imaging. Instead, feasibility to detect human carotids and carotid-sized vessels in clinically-relevant depths is better demonstrated with curved arrays and tomographic approaches.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
In-vivo ; Photoacoustic Tomography ; Ultrasound ; Stenosis ; System ; Artery ; Brain
ISSN (print) / ISBN
1094-4087
e-ISSN
1094-4087
Journal
Optics Express
Quellenangaben
Volume: 20,
Issue: 22,
Pages: 25044-25057
Publisher
Optical Society of America (OSA)
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)