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Next-generation personalized drug discovery: The tripeptide GHK hits center stage in chronic obstructive pulmonary disease.

Genome Med. 4:70 (2012)
Publ. Version/Full Text Volltext DOI PMC
Open Access Gold
ABSTRACT: Chronic lung diseases (CLDs), including chronic obstructive pulmonary disease (COPD), are the second leading cause of death worldwide. The first report of database-driven drug discovery in carefully phenotyped COPD specimens has now been published in Genome Medicine, combining gene expression data in defined emphysematous areas with connectivity-map-based compound discovery. This joint effort may lead the way to novel and potentially more efficient concepts of personalized drug discovery for COPD in particular, and CLD in general.See research article http://genomemedicine.com/content/4/8/67/abstract.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Pathogenesis
Language english
Publication Year 2012
HGF-reported in Year 0
ISSN (print) / ISBN 1756-994X
e-ISSN 1756-994X
Journal Genome Medicine
Quellenangaben Volume: 4, Issue: 8, Pages: , Article Number: 70 Supplement: ,
Publisher BioMed Central
Reviewing status Peer reviewed
POF-Topic(s) 30202 - Environmental Health
Research field(s) Lung Research
PSP Element(s) G-501600-004
G-501600-001
PubMed ID 22999295
Erfassungsdatum 2012-11-29