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Open Access Green as soon as Postprint is submitted to ZB.
Otitis media in infancy and the development of asthma and atopic disease.
Curr. Allergy Asthma Rep. 12, 547-550 (2012)
Otitis media is a frequent respiratory infection of early childhood and it is important to fully understand the long-term complications and sequelae. Literature examining otitis media in early childhood and subsequent development of atopic disease is sparse despite there being vast literature on the association between respiratory infections and atopic disease. Current data support the hypothesis that otitis media infections in early life, especially frequent or severe infections, influence the developing immune system, resulting in increased risk for asthma. Recent findings have also reported an association between otitis media and eczema. Atopic children and those with a family history of atopy appear to be at greater risk. Future work should investigate the specific mechanisms involved. It is possible that vaccines and preventive strategies aimed at reducing the burden of otitis media could also reduce the burden of childhood asthma and atopic disease.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Otitis Media ; Asthma ; Atopy ; Atopic Disease ; Respiratory Infection ; Eczema ; Hygiene Hypothesis ; Infancy; Early Respiratory-infections ; Virus-infection ; Childhood Asthma ; Viral-infections ; School-children ; Ear Infections ; Early-life ; Effusion ; Risk ; Prevalence
ISSN (print) / ISBN
1529-7322
e-ISSN
1534-6315
Quellenangaben
Volume: 12,
Issue: 6,
Pages: 547-550
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institute of Epidemiology (EPI)