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Fast deep-tissue multispectral optoacoustic tomography (MSOT) for preclinical imaging of cancer and cardiovascular disease.
In: Proceedings (SPIE Photons Plus Ultrasound: Imaging and Sensing 2012). Bellingham, USA: SPIE, 2012.:822302 (Proc. SPIE ; 8223)
Optoacoustic imaging has enabled the visualization of optical contrast at high resolutions in deep tissue. Our Multispectral optoacoustic tomography (MSOT) imaging results reveal internal tissue heterogeneity, where the underlying distribution of specific endogenous and exogenous sources of absorption can be resolved in detail. Technical advances in cardiac imaging allow motion-resolved multispectral measurements of the heart, opening the way for studies of cardiovascular disease. We further demonstrate the fast characterization of the pharmacokinetic profiles of lightabsorbing agents. Overall, our MSOT findings indicate new possibilities in high resolution imaging of functional and molecular parameters.
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Publication type
Article: Conference contribution
Editors
Oraevsky, A.A.* ; Wang, L.V.*
Keywords
Optoacoustic Imaging Small Animal Imaging ; Photoacoustic Imaging
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
ISBN
9780819488664
Conference Title
SPIE Photons Plus Ultrasound: Imaging and Sensing 2012
Proceedings Title
Proceedings
Journal
Proceedings of SPIE
Quellenangaben
Volume: 8223,
Article Number: 822302
Series
Proceedings of SPIE
Publisher
SPIE
Publishing Place
Bellingham, USA
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)