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Preparation of Ca-alginate biopolymer beads and investigation of their decorporation characteristics for 85Sr, 238U and 234Th by in vitro experiments.
Radiat. Prot. Dosim. 153, 47-55 (2013)
The aim of this work was to investigate whether Ca-alginate biopolymer beads (CaABBs) can be used to reduce the bioavailability of radionuclides in the gastrointestinal tract of humans. The uptake of strontium, uranium and thorium from a simulated gastrointestinal system was studied by in vitro techniques using CaABBs. This agent was prepared from Na-alginate through cross-linking with divalent calcium ions according to the egg-box model. The effects of process variables such as pH of the gastrointestinal juice, incubation time and solid-to-solution ratio for the removal of radionuclides from the gastrointestinal juice were investigated. The results suggest that CaABBs are a potent material for reducing the bioavailability of radionuclides with a high uptake efficiency in the gastrointestinal tract.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Chelating-agents ; Biosorption ; Metals ; Rats ; Bioaccessibility ; Radiostrontium ; Uranium(vi) ; Absorption ; Speciation ; Efficacy
ISSN (print) / ISBN
0144-8420
e-ISSN
1742-3406
Journal
Radiation Protection Dosimetry
Quellenangaben
Volume: 153,
Issue: 1,
Pages: 47-55
Publisher
Oxford University Press
Publishing Place
Oxford
Reviewing status
Peer reviewed