OpenSSL SSL_connect: Connection reset by peer in connection to v2.sherpa.ac.uk:443 PuSH - Publication Server of Helmholtz Zentrum München: MALDI imaging mass spectrometry for direct tissue analysis.

PuSH - Publication Server of Helmholtz Zentrum München

Meding, S. ; Walch, A.K.

MALDI imaging mass spectrometry for direct tissue analysis.

Methods Mol. Biol. 931, 537-546 (2013)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
MALDI (Matrix-Assisted Laser Desorption/Ionization) Imaging mass spectrometry is a powerful new method for analyzing the spatial distribution of molecules in tissues. Several different classes of cellular constituents such as proteins, peptides, lipids, and small molecules can be analyzed in situ while maintaining the morphological integrity of the tissue. This allows a correlation of the morphology with the previously acquired molecular patterns. By this, specific molecules can be clearly assigned to their cellular origin. Here, we will present a protocol for the analysis of proteins in tissues which are either native or alcohol-fixed and paraffin-embedded.
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Editors Taatjes, D.J.* ; Roth, J.*
Corresponding Author
Keywords MALDI Imaging; Imaging mass spectrometry; In situ proteomics; Tissue proteomics; Morphology-based tissue analysis
ISSN (print) / ISBN 1064-3745
e-ISSN 1940-6029
Conference Title Cell Imaging Techniques : Methods and Protocols
Journal Methods in Molecular Biology
Quellenangaben Volume: 931, Issue: , Pages: 537-546 Article Number: , Supplement: ,
Series Methods in Molecular Biology
Publisher Springer
Publishing Place Berlin [u.a.]
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Pathology (PATH)
Research Unit Analytical Pathology (AAP)