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Intravascular multispectral optoacoustic tomography of atherosclerosis: Prospects and challenges.
Imaging Med. 4, 299-310 (2012)
The progression of atherosclerosis involves complex changes in the structure, composition and biology of the artery wall. Currently, only anatomical plaque burden is routinely characterized in living patients, whereas compositional and biological changes are mostly inaccessible. However, anatomical imaging alone has proven to be insufficient for accurate diagnostics of the disease. Multispectral optoacoustic tomography offers complementary data to anatomical methods and is capable of imaging both tissue composition and, via the use of molecular markers, the biological activity therein. In this paper we review recent progress in multispectral optoacoustic tomography imaging of atherosclerosis with specific emphasis on intravascular applications. The potential capabilities of multispectral optoacoustic tomography are compared with those of established intravascular imaging techniques and current challenges on the road towards a clinically viable imaging modality are discussed.
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Publication type
Article: Journal article
Document type
Review
Keywords
atherosclerosis; intravascular imaging; molecular imaging; multispectral imaging; optical imaging; optoacoustic imaging; photoacoustic imaging; ultrasound
Journal
Imaging Medicine
Quellenangaben
Volume: 4,
Issue: 3,
Pages: 299-310
Publisher
Future Medicine
Non-patent literature
Publications
Institute(s)
Institute of Biological and Medical Imaging (IBMI)