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Open Access Green as soon as Postprint is submitted to ZB.
Challenges of translating genetic tests into clinical and public health practice.
Nat. Rev. Genet. 10, 489-495 (2009)
Research in genetics and genomics has led to an expanding list of molecular genetic tests, which are increasingly entering health care systems. However, the evidence surrounding the benefits and harms of these tests is frequently weak. Here we present the main challenges to the successful translation of new research findings about genotype-phenotype associations into clinical practice. We discuss the means to achieve an accelerated translation research agenda that is conducted in a reasonable, fair and efficient manner.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
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24.185
4.330
58
95
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Special Publikation
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Publication type
Article: Journal article
Document type
Review
Keywords
egapp working group; cost-effectiveness; technology-assessment; reducing morbidity; colorectal-cancer; lynch syndrome; services; care; strategies; disorders
Language
english
Publication Year
2009
HGF-reported in Year
2009
ISSN (print) / ISBN
1471-0056
e-ISSN
1471-0064
Journal
Nature Reviews - Genetics
Quellenangaben
Volume: 10,
Issue: 7,
Pages: 489-495
Publisher
Nature Publishing Group
Reviewing status
Peer reviewed
POF-Topic(s)
30202 - Environmental Health
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-505300-001
DOI
10.1038/nrg2606
Scopus ID
67649732906
PubMed ID
19506575
Erfassungsdatum
2009-12-31