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Schmidt, W.-P.* ; Roesler, A.* ; Kretzschmar, K.* ; Ladwig, K.-H. ; Junker, R.* ; Berger, K.*

Functional and cognitive consequences of silent stroke discovered using brain magnetic resonance imaging in an elderly population.

J. Am. Geriatr. Soc. 52, 1045-1050 (2004)

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Open Access Green as soon as Postprint is submitted to ZB.

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Objectives: To evaluate the prevalence of silent stroke and its associated consequences on physical, cognitive, and emotional functioning in an elderly population. Design: Population-based cross-sectional survey. Setting: The Memory and Morbidity in Augsburg Elderly project in the Augsburg region of southern Germany. Participants: Two hundred sixty-seven community-dwelling persons aged 65 to 83. Measurements: The presence of silent stroke was determined using magnetic resonance imaging brain scan and a single question asking for physician-diagnosed stroke in each participant. The health effect of silent stroke was assessed using rating scales for self-perceived health status (36-item short-form health survey), activities of daily living (ADLs) and instrumental ADLs, cognitive function, and depression (Center for Epidemiologic Studies Depression scale). Results: Just fewer than 13% (12.7%) of participants were affected by silent stroke. Silent stroke was associated with a history of hypertension, heart surgery, and elevated C-reactive protein. Individuals with silent stroke showed impairments on the Mini-Mental State Examination test and in the cognitive domains of memory, procedural speed, and motor performance. Conclusion: The presence of silent stroke has a considerable effect on cognitive performance in those affected. Determining the presence of silent stroke using brain imaging may contribute to identifying individuals at risk for developing gradual neurological deficits.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords stroke; silent; cognitive function; activities of daily living; depression

ISSN (print) / ISBN 0002-8614

e-ISSN 1532-5415

Journal Journal of the American Geriatrics Society

Quellenangaben Volume: 52, Issue: 7, Pages: 1045-1050

Publisher Wiley

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Epidemiology (EPI)