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Mouse mutants as models for congenital retinal disorders.
Exp. Eye Res. 81, 503-512 (2005)
Animal models provide a valuable tool for investigating the genetic basis and the pathophysiology of human diseases, and to evaluate therapeutic treatments. To study congenital retinal disorders, mouse mutants have become the most important model organism. Here we review some mouse models, which are related to hereditary disorders (mostly congenital) including retinitis pigmentosa, Leber's congenital amaurosis, macular disorders and optic atrophy.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
animal model; retina; mouse; gene mutation; retinal degeneration
ISSN (print) / ISBN
0014-4835
e-ISSN
1096-0007
Journal
Experimental Eye Research
Quellenangaben
Volume: 81,
Issue: 5,
Pages: 503-512
Publisher
Elsevier
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Developmental Genetics (IDG)