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Assignment of isochores for all completely sequenced vertebrate genomes using a consensus.

Genome Biol. 9:R104 (2008)
Publ. Version/Full Text Volltext DOI PMC
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We show that although the currently available isochore mapping methods agree on the isochore classification of about two-thirds of the human DNA, they produce significantly different results with regard to the location of isochore boundaries and isochore length distribution. We present a new consensus isochore assignment method based on majority voting and provide IsoBase, a comprehensive on-line database of isochore maps for all completely sequenced vertebrate genomes.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords DENSITY GRADIENT CENTRIFUGATION; FISH GENOMES; COMPUTATIONAL PREDICTION; INTERSPERSED REPEATS; EUKARYOTIC GENOMES; GENE DISTRIBUTION; DNA-SEQUENCES; NONCODING DNA; GC CONTENT; ORGANIZATION
ISSN (print) / ISBN 1474-760X
e-ISSN 1465-6906
Journal Genome Biology
Quellenangaben Volume: 9, Issue: 6, Pages: , Article Number: R104 Supplement: ,
Publisher BioMed Central
Non-patent literature Publications
Reviewing status Peer reviewed